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you are here: Home » Our Students » 2007-2009 2007-2009
Bauer, Kathrin Maria
City and country of origin: Educational background: International Master's Programme:
Main scientific interest: Project Internships Functional Interaction between frataxin and glial lazarillo Regulation spannungsabhängiger Ca2+-Kanäle durch Bestrophin-1 Comparative assessment of vigilance
Bär, Julia
City and Country of origin: Educational background:
Main scientific interests
1. Molecular imaging of TGF-beta mediated effects on adult neurogenesis Master project Influence of chronic psychosocial stress on anxiety-related behaviour and molecular parameters of the brain Future Plans and objectives
Brockmann, Marisa
City and Country of origin: Educational background:
Main scientific interests Neurodegenerative processes; higher brain functions like memory Project Practicums Effects of Acute and Chronic Oxytocin treatment on anxiety-related behaviour LPHN-3 a novel candidate gene for ADHD Einfluss von verhaltenssteuernden Neuropeptiden auf die elektrophysiologische Aktivität hypothalamischer Neurone
Finger, Beate Christina
City and Country of origin: Educational background:
Project Internships 1. Effects of neuropeptide S (NPS) injected in the medial amygdala on affective behaviours 2. Anxiolytic and antidepressant effects of NPS in Flinders sensitive line rats 3. Molecular characterization of NPS Publications Cassaday HJ, Finger BC & Horsley RR. Methylphenidate and nicotine focus responding to an informative discrete CS over successive sessions of appetitive conditioning. Journal of Psychopharmacology 2007, in press
Ishiyama, Shimpei
City and Country of origin: Educational background:
Main scientific interests
Project Internships Modulation of voltage-gated calcium channels by Rab27a Considering some methodological problems in social neuroscience Electrophysiological characterization of cerebellar NG2 glia in TgH (NG2-EYFP) mice Master project Regulatory interaction between voltage-dependent Ca2+ channels and Rab-GTPase in RPE Future Plans and objectives Master of Science in Neurosciences PhD in Neurosciences
Kiem, Sara Alessia
City and Country of origin: Educational background:
Main scientific interests
Project Internships 1. Neural correlates associated with Theory of Mind and Inhibition 2. Simultaneous EEG/fMRI recording of neural responses to passive oddball stimulation while shifting tone probabilities 3. MR-spectroscopic testing of cerebral metabolic changes after sleep deprivation Master project Neural Correlates of Belief Attribution and Inhibition Summary: The concept of having a Theory of Mind (ToM) originally comes from the field of developmental psychology, referring to the ability to represent false beliefs, which is the ability to recognize that others can have beliefs about the world that are not corresponding to reality. The acid test for investigating the ability to attribute beliefs is the true belief/false belief task (FB/TB task). During this task the participants have to select among interfering responses concerning true or false mental representations of the reality. Interestingly, in children the ability to understand false belief develops to the same time as inhibitory control. This issue has been intensively studied in behavioural and, during the last decade, also neuroimaging studies and raised the question, if belief attribution (as the crucial part of Theory of Mind) and cortical inhibition, needed to suppress a prepotent response, are supported by overlapping brain areas. Possible candidate regions seem to be the dorsal medial prefrontal cortex (including the dorsal anterior cingulate cortex) and the right temporo-parietal junction. But so far, only one experiment was performed investigating belief attribution and inhibition in the same session using equal stimuli (Rothmayr, Dissertation). The present functional Magnetic Resonance Imaging (fMRI) study used the same complex social stimuli to compare activation in the following two tasks: 1) 14 volunteers performed a modified Theory of Mind task, originally known from developmental psychology studies (Sally-Anne-Paradigm; Baron-Cohen et al., 1985), tapping belief attribution by comparing stories involving another person’s false belief with stories involving another person’s true belief; 2) A Simon task, originally invented to study response-based conflicts caused by interfering response possibilities. For this latter experiment a total of 28 volunteers participated out of which 16 performed the task while being in the MRI scanner. False belief over true belief revealed activation in the medial prefrontal cortex (BA 8; including the dorsal anterior cingulated cortex; BA 32), the dorsolateral prefrontal cortex (BA 9) and the temporo-parietal junction bilaterally (BA39/40). Resolution of the response-based conflict (incompatible trials > compatible trials) was distinguished by activity in the frontal eye field (BA 8), the visual cortex (BA 18/19), the right temporo-parietal junction (BA 39), as well as in parts of the ventrolateral prefrontal cortex (BA 38/47). The graphical overlap of the results revealed non-overlapping regions for false belief and inhibition in the dorsomedial prefrontal cortex (BA 8/32) and in the right temporo-parietal junction (BA 39). Future Plans and objectives Find an interesting PhD Project at the intersection between biology and psychology
Marek, Roger
City and Country of origin: Educational background:
Main scientific interests Neurodegenerative diseases, Neurochemistry Project Practicums Cortical Excitation by Transcranial Magnetic Stimulation (TMS) and the Association to Allelic Variants of the 5-HT Transporter
Effect of chronic stress on circadian rhythmicity versus effects of diurnal rhythmicity on stress outcome
Coupling within SCN neurones and K-current recordings in Kv-KO mice
Regensburger, Martin
City and Country of origin: Educational background:
Main scientific interests Use of stem cells to model and cure neural diseases Project Internships 1. Comprehensive characterization of polyclonal antibody anti-best1, specific to the N-terminal region of bestrophin1 2. Cloning of Disabled-2 into a mammalian expression vector 3. Adult neurogenesis in transgenic animal models of hereditary DYT1 dystonia Master project The cell-autonomous effects of alpha-synuclein on adult neuronal development. Future Plans and objectives
Santos, Edgar Marcial
City and Country of origin: Educational background:
Main scientific interests
Project Internships 1. Cellular responses of adult neural progenitors to Conective Tissue Growth Factor 2. Neuropsychological screening and biomarkers in neurodegenerative disorder 3. Regulation of T cell differentiation to encephalitogenic phenotypes by Smad7 Future Plans and objectives Publications Calva-Rodriguez R, Luna-Alcantara JJ, Lagunes-Yannelli B, Rivera-Dominguez ME, Calva-Cerqueira D, Santos-Marcial E. Prevalence and risk factors of Helicobacter pylori infection in three populations of children in Puebla, Mexico. Rev Gastroenterol Mex. 2006; 71(4):440-5. Spanish. Fernandez-Tamayo N, Flores-Villa R, Blanco-Aguilar J, Duenas-Arau Mde L, Pena-Flores Mdel P, Rubio-Calva C, Santos-Marcial E. Crusted scabies (Norwegian scabies) a case report. Gac Med Mex. 2006; 142(6):507-10. Spanish.
Steffenhagen, Carolin
City and Country of origin: Educational background:
Main scientific interests Neuroscience, especially the neurobiological mechanisms which underlie human behaviour, Genetics Project Internships 1. Loss of function analysis of genes related to frataxin in drosophila 2. Mesenchymal stem cells and fetal neural progenitors interactions: Oligodendrogenesis? 3. Transcranial Magnetic Stimulation for measuring and modulating neuronal cortical activit
Tembei, Forkwa Kieran
City and Country of origin: Educational background:
Main scientific interests I am very much interested in the use of advanced molecular biology techniques in research. Using them to elucidate the cellular/molecular basis of disease and behaviour are my main interest. Project Internships 1. Cognitive impairments related to driving ability after partial sleep deprivation 2. Does oxytocin regulate social behaviours in male rats? 3. Effects of chronic psycho-social stress on light sensitivity and retinal atrophy Future Plans and objectives
Toth, Iulia
City and Country of origin: Educational background:
Main scientific interests Clinical disorders involving social functioning deficits 1. Effects of chronic psycho-social stress on light sensitivity and retinal atrophy 2. Behavioral differences in the forced swim test and passive avoidance extinction in two substrains of C57BL/6 mice 3. Role of the neuropeptide oxytocin in social behaviours
Tse, Mei Ling Ada
City and Country of origin: Educational background:
Main scientific interests Molecular & Cellular basis of perception & higher cognitive functions, Neurogenesis & Neurodevelopment Project Internships During the ECN Programme: 2. Neurocorrelates of auditory aftereffect – zwicker tone 3. Auditory Event-Related Potentials of Brief Sound Bursts During Zwicker Tone Perception At the Chinese University of Hong Kong: Functional MRI correlates of the Zwicker tone – an auditory aftereffect Future Plans and objectives: Publications 1. “Hepatitis B virus genotype has no impact on hepatitis B e antigen seroconversion after lamivudine treatment.” World Journal of Gastroenterology 9 (12): 2695-2697 DEC 2003 2. “Genotype C Hepatitis B Virus Infection is associated with increased risk of Hepatocellular Carcinoma.” GUT 53(10): 1494-1498 OCT 2004 3. “Genetic Polymorphisms of Interleukin-1-Beta in Association with Sustained Response to Anti-viral Treatment in Chronic Hepatitis B in Chinese.” Alimentary Pharmacology & Therapeutics 23 (12): 1703-1711 JUN 15 2006 4. “Metabolic and adipokine profile of Chinese patients with non-alcoholic fatty liver disease.” Clinical Gastroenterology and Hepatology 4(9):1154-1161 SEP 2006 5. “RNA Interference Targeting X protein of Hepatitis B Virus Suppresses Tumor Growth and Enhances the Cisplatin Chemosensitivity in Human Hepatocellular Carcinoma.” Cancer Letters 2007 Aug 8;253(1):43-52. 6. “Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response.” Clinical Gastroenterology & Hepatology. 2007 Dec;5(12):1462-8 7. “Association of cytokine gene polymorphisms and liver fibrosis in chronic hepatitis B.” Journal of Gastroenterology & Hepatology. 2008 May;23(5):783- 8. “Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese.” Journal of Gastroenterology and Hepatology. 2008 Jun;23(6):914-21 9. “Validation of the NAFLD fibrosis score in a Chinese population with low prevalence of advanced fibrosis.” American Journal of Gastroenterology. 2008 Jul;103(7):1682-8 |
Highlights 2007-2009:Weekendseminar Feb 15 - 17, 2008: |
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