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2006-2008
| Chiu, Wei-Hua | Taiwan |
| Chiucu, Andrei | Romania |
| Dinnbier, Matthias | Germany |
| Ernst, Wolfgang | Germany |
| Heckel, Andreas | Germany |
| Karl, Alexandra | Germany |
| Konstandin, Nicola | Germany |
| Marxreiter, Franz | Germany |
| Nafees, Ahmad | Pakistan |
| Nyuyki, Kewir | Cameroon |
| Pilsl, Anna | Germany |
| Sinning, Anne | Germany |
| Wagner, Katrin | Germany |
Chiu, Wei-Hua
City and country of origin: Kaohsiung, Taiwan (R.O.C.)
Educational background:
Physical Therapy, National Yang-Ming University
International Master's Programme: Experimental and Clinical Neurosciences
Main scientific interest:
I’m interested in the
neurogenesis and neuroinflammation in the normal or pathological environment
Project Practicums:
- Oxidative stress in a Drosophila model of Friedreich’s
ataxia and new model of RNAi-mediated suppression of frataxin
Supervision: Dr. Juan Navarro and Prof. S. Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg - Does the Secretory
leukocyte protease inhibitor” influences the proliferation or maturation of oligodendroglia
cell lines?
Supervision: Dr. Andre Mueller and Dr. A. Steinbrecher
Department of Neurology, University of Regensburg - Cloning and Expressing the T
cell receptors of Myasthensia Gravis patients on hybridoma cells
Supervision: Dr. K. Dornmair and Prof. H. Wekerle
Department of Neuroimmunology, Max-Planck Institute, Neurobiologyp
Master project
- Title:"Expression analysis and functional analysis of doublecortin-like molecules in neuronal stem and progenitor cells."
- Aim of the study: The project is to analyse the expression of doublecortin-like proteins in neuronal stem and progenitor cells and to investigate their function in these cells.
- Supervision: Dr. S. Couillard-Despres and Prof. L.Aigner Department of Neurology
Chiucu, Andrei
City and country of origin: Calarasi, Romania
Educational background:
Faculty of General Medicine, University of
Medicine and Pharmacy „Carol Davila“, Bucharest, Romania
International Master's Programme: Experimental and Clinical Neurosciences
Main scientific interest:
I’m interested in the
neurogenesis and neuroinflammation in the normal or pathological environment.
Project Practicums:
- Phenotype analysis of WDR36 knockout mice
Supervision: Prof. Dr. Ernst Tamm
Human Anatomy and Embryology University of Regensburg - Isolated brain perfusion model
Supervision: Dr. Felix Schlachetzki
Department of Neurology, University of Regensburg - Evaluation of the efficiency of the Human
Caspase3 Ab in Drosophila embryos
Supervision: Prof. Stefan Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg
Dinnbier, Matthias
City and country of origin:
Regensburg, Germany
Educational background:
First Diploma in Psychology, University of
Regensburg, Germany
International Master's Programme
Experimental and Clinical Neurosciences
Main scientific interest:
- Human Sensory Processes (Visual Perception, Object Perception, Multisensory Processes)
- Higher Cognitive Functions
(Attention, Learning, Memory)
Project Practicums
- The Influence of Mood on
the Recognition of Emotions
Supervision: Dr. Alexa Veenema, Prof. Dr. Mark Greenlee
Department of Behavioral Neuroendocrinology and Department of Experimental Psychology, University of Regensburg - Segmentation of Simple
Objects: Serial Processing or Holistic Perception?
Supervision: Drs. Ilia Korjoukov, Prof. Dr. Pieter R. Roelfsema
Vision Cognition Group, Netherlands Institute of Neuroscience, Royal Dutch Academy of Sciences,
Amsterdam, The Netherlands - Serial Processing
Effects in Mental Tracing of Simple Prolonged Objects
Supervision: Drs. Ilia Korjoukov, Prof. Dr. Pieter R. Roelfsema
Vision Cognition Group, Netherlands Institute of Neuroscience, Royal Dutch Academy of Sciences,
Amsterdam, The Netherlands
Future Plans and objectives
- University Diploma in Psychology
- Master of Science in Neurosciences
- Doctoral Studies in Psychology or Neurosciences
- Scientific Career in Psychology and Neurosciences
City and country of origin:
Ruhpolding, Germany
Educational background:
- 1992-2001, Chiemgau
Gymnasium Traunstein - since 2002, Biology,
University of Regensburg - International Master's Programme:
Experimental and Clinical Neurosciences
Main scientific interest:
Research on stem cells as therapy for certain diseases
Project Practicums:
- Expression analysis of doublecortin family members in adult neural stem cells
Supervision: Dr. Sebastien Couillard-Després
- Neurodegeneration in the PNS of Drosophila and Expression of TOR in wt and frataxin overexpressing flies
Supervision: Dr. Juan Navarro, Prof. Dr. Stefan Schneuwl
Department of developmental Biology, Institute of Zoology, University of Regensburg
- TYROBP promoter study in Macrophages
Supervision: Dr. Thomas Langmann
Human Genetics, University of Regensburg
Master project
Title:
Molecular
characterization of dental precursor cells during retinal differentiation in
vitro
Supervision: Dr. Christian Morsczeck, Human
Genetics, University of Regensburg
City and Country of origin:
Regensburg, Germany
Educational background:
Medical Program, University of Regensburg
International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
- Illusions
- Multisensory Integration
- Computational Neuroscience
Project Practicums
Multisensory Integration
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg
Compensation of fixational Eye Movements
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg
Flow parsing Hypothesis
Supervision: Department of Neural Information Processing, Ulm
Master project
Title: Mulitsensory Integration – a neurophysiological Model
Aim of the study:
We test a recent model of auditory-visual integration and segregation. Task-dependent superposition and segregation of neural activity is described by modeling the functioning of multimodal neurons
Supervision: Prof. Dr. Mark Greenlee
Department of Experimental Psychology, University of Regensburg
City and Country of origin:
Munich, Germany
Educational background:
Biology Diploma, University of Regensburg
International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
- Adult neurogenesis
Project Practicums
Influence of a dopamine D3 receptor agonists on adult hippocampal neurogenesis
Supervision: Dr. Beate Winner, Prof. Dr. Jürgen Winkler
Department of Neurology, University of Regensburg
Influence of the PI3 kinase signalling pathway on proliferation of adult neural stem cells
Supervision: Dr. Chichung Lie
Department of Developmental Biology, GSF, Munich
Influence of different transcription factors on neurite outgrowth in a cell culture of cerebellar granule neurons
Supervision: Dr. Armin Blesch
Department of Neurosciences, University of California, San Diego, USA
Master project
Title: Influence of the PI3Kinase / mTOR signaling pathway on adult neural stem cells
Future Plans and objectives:
PhD
City and Country of origin:
Regensburg, Germany
Educational background:
Biology Diploma, University of Regensburg
International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
I’m interested in molecular biology, especially in the field of neuroscience. Focusing on genetics.
Project Practicums
Effects of chronic stress on late pregnancy and lactation in rats
Supervision: Dr. David Slattery, Prof. Dr. Inga Neumann
Department of Molecular and Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg
Investigations on VMD2 –Immortalization of primary cells
Supervision: Dr. Florian Rauscher, Prof. Dr. Bernhard Weber
Institute of Human Genetics, University of Regensburg
Effects of Single Nucleotide Polymorphism RS2070951 on Human Mineralcorticoid Receptor A and B expression
Supervision: Nienke van Leeuwen, Dr. Roel de Rijk, Prof. Dr. Ron de Kloet
Division of Medical Pharmacology. Gorlaeus Laboratory, University of Leiden, The Netherlands
Master project
Title: Molecular and phenotypic characterization of a Bestrophin deficient mouse model
Supervision: Prof. Dr. Bernhard Weber
Institute of Human Genetics, University Regensburg
Future Plans and objectives
The nearest future plans are to finish the ECN program successfully and afterwards starting my PHD. I think doing the PHD abroad would be nice.
City and Country of origin:
Regensburg, Germany
Educational background:
Medicine, University of Regensburg
International Master's Programme
'Experimental and Clinical Neurosciences'
Email: franz.marxreiter@gmail.com
Main scientific interest:
Adult neurogenesis, neuronal stem cells, neurodegenerative diseases
Project Practicums
1) Adult olfactory bulb neurogenesis in an alpha-synuclein expressing mouse model
Supervisors: Prof Jürgen Winkler; Dr. Beate Winner
University of Regensburg
2) Regulation of DCX expression by miRNA's in embryonic neuronal progenitor cells
Supervisors: Prof Ludwig Aigner, Dr. Sébastien Couillard-Despres
University of Regensburg
3) Evaluation of ß-catenin mediated regulation of Sox2
Supervisors: Dr. Chichung Lie, Dr. Lucia Berti
Helmholtz Zentrum München
Master project
Title: A30P alpha-synuclein regulates adult olfactory bulb neurogenesis
Aim of the study: Hyposmia is an important and early premotor symptom in Parkinson’s disease (PD). In PD brains, alpha-synuclein pathology is present in the olfactory bulb (OB). In addition, the OB is an active region of adult neurogenesis, where newly generated neurons physiologically integrate. While accumulation of wildtype alpha-synuclein is one of the pathogenic hallmarks of non-genetic forms of PD, the A30P alpha-synuclein mutation results in an earlier disease onset. Recent work indicated that olfactory neurogenesis is decreased in adult transgenic models of synucleinopathies due to a decreased survival of newly generated neurons. Nothing so far is known about the effects of A30P alpha-synuclein on adult neurogenesis or if halting expression of alpha-synuclein could reverse the previously described decrease in adult neurogenesis. This lead to the idea to study adult neurogenesis in the subventricular zone (SVZ)/OB system in a tetracycline suppressive (tet-off) transgenic model, expressing human mutant A30P alpha-synuclein under the control of the Calcium/Calmodulin dependent Kinase 2 alpha (CaMK II) promoter which allows transient suppression of the alpha-synuclein transgene. This project can (1 )provide insights into mechanisms of early cellular dysfunction induced by alpha-synuclein, (2) foster the understanding of alpha-synuclein mediated reduction of cellular plasticity. Both points might be crucial events in the pathogenesis of PD and in turn are promissing tools for future therapeutic strategies.
Supervision: Prof. Jürgen Winkler, Dr. Beate Winner
Department of Neurology, University of Regensburg
City and Country of origin:
Gujranwala, Pakistan
Educational background:
M.Phil (Molecular Biology) CEMB
University of the Punjab, Lahore Pakistan
M.Sc.(Zoology) Govt. College
University Lahore, Pakistan
International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
Human Genetics, Molecular Biology, Biomedical
Project Practicums
Development of animal model for Human autosomal dominant Retinitis Pigmentosa
Supervision: Dr. Juan Navaro, Prof. Dr. Stefan Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg
Effect of Chronic Stress on Physiological and Molecular adaptations in virgin and pregnant rats
Supervision: Dr. David Slattery, Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg
Screening for Polymorphisms in CRH gene
Supervision: Prof. Dr. Rainer Landgraf
Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
Master project
Title:
Screening for Genetic factors responsible for Thalassemia Intermedia in Pakistan
Supervision: Dr. Shaheen N. Khan
National Center of Excellence in Molecular Biology, University of the Punjab, Lahore Pakistan
Title:
Genotyping of the anxiety related genes
Supervision: Prof. Dr. Rainer Landgraf
Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
Future Plans and objectives
To be a researcher to study the diseased genes and their interaction with the environment
Current position: PhD-student
Title:
Functional analysis of the Pitx3 signalling in mutant mouse aphakia: a model of hereditary micropthalmie and Parkinson disease
Supervisor: Prof. Dr. Joachen Graw
Institute: Institute of Developmental Genetics, Helmholtz Center Munich, German Research Center for Environmental Health
Neuherberg, Germany
City and Country of origin:
Sop, Cameroon
Educational background:
- CGCE; O_level, Government Bilingual High School
Jakiri, Cameroon - CGCE; A_level, Saint Augustine's College
Kumbo, Cameroon - BSc. Biochemistry; Medical laboratory Technology Buea University, Buea, Cameroon
International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
I look up to getting an insight of the neurobiological mechanisms which underlie human behaviour (anxiety/depression) and why not thee pathological transits involving neurodegenerative disorders
Project Practicums
Effects of Colour Perception on Auditory and Somato sensory perception
Supervision: Dr. B. Langguth, Dr. M. Landgrebe, Dr. P. Eichhammer
Department for Psychiatry and Psychotherapy, University of Regensburg
Expression Analysis of Antioxidant Enzymes in Transgenic Drosophila melanogaster
Supervision: Dr. Juan A. Navarro, Prof Dr. S. Schneuwly
Department of Developmental Biology, Institute of Zoology, University of Regensburg
Brain Oyxtocin Mediated Effects of mating on anxiety related behavior in female Wistar rats
Supervision: Martin Waldherr, Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg
Master project
Title:
Brain Oxytocin mediated effects of mating on anxiety related behavior in genetically modified HAB/LAB male rats
Aim of the study: Sexual activity is a physiological stimuli, like any other stimuli (lactation, parturition), triggering release of the neuropeptide Oxytocin from the magnocellular neurons of the hypothalamic Supraoptic Nucleus(SON) and Paraventricular Nucleus(PVN). The anxiolytic receptor mediated effects of this neuropeptide have been shown in males (PVN and Central Amygdala) after mating (Waldherr and Neumann, unpublished) but nothing is known so far, about its effects on inborn genetically modified rats. My interest then proceeds, with a keen attention in long term behavioural impacts.
Supervision: Prof. Dr. Inga Neumann
Department of Molecular an Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg
Future Plans and objectives
Behavioural Neuroendocrinology is an interesting branch of Neuroscience, relating daily actions/reactions with neurobiological mechanisms. Specializing as a behavioural Neuroscientist in the advanced academic ladder will be my point my interest. But as flexible as science can be, clinical neurosciences is another line of interest, as a lot of diseases are traced to be of neurobiological origin
City and Country of origin:
Munich, Germany
Educational background:
- Biology Diploma, University of Regensburg
- Bachelor of Science in Biology
- International Master's Programme
'Experimental and Clinical Neurosciences'
Email: anna_pilsl@yahoo.de
Main scientific interest
Molecular Mechanisms involved in Neurodegenerative Diseases
Project Practicums
Molecular Analysis of Sorsby Fundus Dystrophy Mutation Timp3S156C
Supervision: Prof. Dr. Bernhard Weber
Institute of Human Genetics, University Hospital of Regensburg
Effects of Connective Tissue Growth Factor (CTGF) on Extracellular Matrix Composition
Supervision: Prof. Dr. Ernst Tamm
Institute of Human Anatomy, University of Regensburg
Identification of Tau-transgenic Zebrafish
Supervision: Prof. Dr. Christian Haass
Laboratory for Alzheimer's and Parkinson's Disease Research, Ludwig-Maximilians-University Munich
Master project
Title: “Establishment of a Transgenic Zebrafish Model to Study the Neuroprotective Activity of Parkin in vivo”
Aim of the study: Parkinson's disease (PD) is the most common movement disorder and the second most common neurodegenerative disease after Alzheimer's disease. The pathological hallmark of PD is a specific loss of dopaminergic neurons in the substantia nigra pars compacta, resulting in a variety of symptoms including rigidity, resting tremor, bradykinesia and postural instability. Only recently it has been discovered that, besides environmental factors, also genetic mutations play a major role in about 20% of all PD cases. One of the genes involved in PD, the parkin (PARK2) gene, encodes a 465 amino acid protein with an ubiquitin-like domain (UBL) at the N-terminus and a RING box close to the C-terminus. Parkin acts as an E3 ubiquitin ligase catalyzing the transfer of ubiquitin moieties to target proteins. Through activation of the NF-kB pathway, Parkin appears to be a potent neuroprotecting agent. Using the advantages of the zebrafish (Danio rerio) model system we now plan to assess Parkin´s neuroprotective capacity and biochemical function in a novel animal model.
For further information visit:
http://haass.web.med.uni-muenchen.de/Research/NBC/index.html
Supervision: Dr. Konstanze Winklhofer
Ludwig-Maximilians-University Munich, Department of Biochemistry
City and Country of origin:
Kassel, Germany
Educational background:
- BSc. Molecular Biology, University of Mainz, Germany
- International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
I am interested in physiological and especially electrophysiological properties of neurons enabling its unique and miscellaneous signaling within the brain and possible implications for various diseases
Project Practicums
Identification of Ca2+activated Cl--channels in epithelial cells: Bestrophin
Supervision: Dr. K. Kunzelmann
Department of Physiology, University of Regensburg
Connective Tissue Growth Factor and Glaucoma
Supervision: Prof. Dr. E. Tamm
Department of Anatomy and Embryology, University of Regensburg
Influence of intracellular calcium levels on circadian rhythms in mammals
Supervision: Dr. S. Michel
Department of Neurophysiology, University Medical Center Leiden, Leiden, The Netherlands
Master project
Title: Influence of membrane properties on expression of circadian rhythms in mammalian central pacemaker neurons
Aim of the study: The mammalian circadian clock is driven by a molecular machinery residing in central pacemaker neurons in a part of the hypothalamus known as the suprachiasmatic nucleus (SCN). Until recently, the role of membrane excitability for the circadian clock has been restricted to input and output. But there is increasing evidence that it is crucial for the maintenance of rhythmicity within the SCN. Aim of my master thesis is to obtain further insights into the of role calcium signaling and membrane excitability for the circadian rhythm in mammals.
Supervision: Dr. S. Michel
Department of Neurophysiology, University Medical Center Leiden, Leiden, The Netherlands
Future Plans and objectives
After a successful completion of my master thesis in Leiden I hope to perform a PhD thesis and enlarge my knowledge in the field of (electro-) physiology
Current position: PhD-student
Title: Functional analysis of anion exchangers in different transgene mouse models
Supervisor: Prof. Dr. C.A. Hübner
Institute: Institute of Clinical Chemistry, Clinic University Jena, Jena, Germany
City and Country of origin:
Geraberg, Germany
Educational background:
- Biology Diploma, University of Regensburg
- International Master's Programme
'Experimental and Clinical Neurosciences'
Main scientific interest
Neuroscience, Genetics
Project Practicums
Is the oxytocin-induced activation of ERK 1/2 pathway within the hypothalamus mediated by endocannabinoid receptor type 1?
Supervision: Dr. Annegret Blume, Prof. Dr. Inga Neumann
Department of Molecular and Behavioural Neuroendocrinology, Institute of Zoology, University of Regensburg
Molecular Characterization of Microglia Activation related to Retinal Degeneration
Supervision: Dr. Thomas Langmann
Institute of Human Genetics, University of Regensburg
The effects of prolactin on stress induced CRH expression
Supervision: Prof. Dr. Greti Aguilera
National Institutes of Health, Developmental Endocrinology Branch, NICHD, Bethesda, Maryland, USA
Master project
Title: Regulation of adult neural progenitor cell proliferation by stress-related molecules in vitro
Supervision: Prof. Dr. Ludwig Aigner
Department of Neurology, University Clinic of Regensburg
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